A propensity score-matched comparison between Cardia and Amplatzer PFO closure devices - insights from the SOLUTION registry (Swiss percutaneOus patent foramen ovale cLosUre in recurrent clinical events prevenTION)

Puricel, Serban-George; Arroyo, Diego Andoni; Goy, Jean-Jacques; Praz, Fabien; Palhais, Nuno; Wahl, Andreas; Stauffer, Jean-Christophe; Togni, Mario; Berger, Alexandre; Meier, Bernhard; Cook, Stéphane (2014). A propensity score-matched comparison between Cardia and Amplatzer PFO closure devices - insights from the SOLUTION registry (Swiss percutaneOus patent foramen ovale cLosUre in recurrent clinical events prevenTION). EuroIntervention, 11(2), pp. 230-237. Europa Digital & Publishing 10.4244/EIJY14M05_05

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Aims: To compare clinical outcome of Amplatzer PFO (APFO) to Cardia PFO (CPFO) occluder. Percutaneous patent foramen ovale (PFO) closure prevents stroke recurrence in stroke due to paradoxical embolism. Methods and results: The primary endpoint was a composite of stroke, TIA, or peripheral embolism at follow-up. The secondary endpoint was residual shunt. Outcome was compared among 934 (APFO: 712; CPFO: 222) patients, and in 297 propensity score-matched patients. The primary endpoint occurred in 29 patients (0.71/100 patient-years): four (2%) with the CPFO (0.31/100 patient-years), and 25 (4%) with the APFO (0.89/100 patient-years) (p=0.20). Residual shunt at six months was more frequent with the CPFO (31% versus 9%, p<0.001). No differences in residual shunts were seen at the last available echocardiographic follow-up (9±18 months): APFO 11%, CPFO 14%, p=0.22. Conclusions: This study suggests that PFO closure with APFO or CPFO is equally effective for the prevention of recurrent events. Residual shunt was more frequent at six months with CPFO, but was similar to APFO at later follow-up.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Puricel, Serban-George; Arroyo, Diego Andoni; Praz, Fabien; Wahl, Andreas and Meier, Bernhard

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1774-024X

Publisher:

Europa Digital & Publishing

Language:

English

Submitter:

Diego Andoni Arroyo

Date Deposited:

13 Oct 2014 15:42

Last Modified:

26 Jun 2016 01:55

Publisher DOI:

10.4244/EIJY14M05_05

PubMed ID:

24830681

BORIS DOI:

10.7892/boris.59143

URI:

https://boris.unibe.ch/id/eprint/59143

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