Innate immune cells express IL-17A/F in acute generalized exanthematous pustulosis and generalized pustular psoriasis.

Kakeda, Masato; Schlapbach, Christoph; Danelon, G; Tang, M M; Cecchinato, V; Yawalkar, Nikhil; Uguccioni, M (2014). Innate immune cells express IL-17A/F in acute generalized exanthematous pustulosis and generalized pustular psoriasis. Archives of dermatological research, 306(10), pp. 933-938. Springer 10.1007/s00403-014-1488-0

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Acute generalized exanthematous pustulosis (AGEP) and generalized pustular psoriasis (GPP) are rare pustular skin disorders with systemic involvement. IL-17A/F is a proinflammatory cytokine involved in various neutrophilic inflammatory disorders. Here we show that IL-17A/F is highly expressed by innate immune cells such as neutrophils and mast cells in both AGEP and GPP.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology

UniBE Contributor:

Kakeda, Masato; Schlapbach, Christoph and Yawalkar, Nikhil

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0340-3696

Publisher:

Springer

Language:

English

Submitter:

Monika Schenk

Date Deposited:

16 Apr 2015 15:26

Last Modified:

19 Oct 2015 11:29

Publisher DOI:

10.1007/s00403-014-1488-0

PubMed ID:

25030504

BORIS DOI:

10.7892/boris.59189

URI:

https://boris.unibe.ch/id/eprint/59189

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