Increasing incidence of canine leptospirosis in Switzerland.

Major, Andrea; Schweighauser, Ariane; Francey, Thierry (2014). Increasing incidence of canine leptospirosis in Switzerland. International journal of environmental research and public health, 11(7), pp. 7242-7260. Molecular Diversity Preservation International MDPI 10.3390/ijerph110707242

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A marked increase in canine leptospirosis was observed in Switzerland over 10 years with a peak incidence of 28.1 diagnosed cases/100,000 dogs/year in the most affected canton. With 95% affected dogs living at altitudes <800 m, the disease presented a seasonal pattern associated with temperature (r2 0.73) and rainfall (r2 0.39), >90% cases being diagnosed between May and October. The increasing yearly incidence however was only weakly correlated with climatic data including number of summer (r2 0.25) or rainy days (r2 0.38). Serovars Australis and Bratislava showed the highest seropositivity rates with 70.5% and 69.1%, respectively. Main clinical manifestations included renal (99.6%), pulmonary (76.7%), hepatic (26.0%), and hemorrhagic syndromes (18.2%), leading to a high mortality rate (43.3%). Similar to the human disease, liver involvement had the strongest association with negative outcome (OR 16.3). Based on these data, canine leptospirosis presents similar features and severity as the human infection for which it therefore can be considered a model. Its re-emergence in a temperate country with very high incidence rates in canines should thus be viewed as a warning and emphasize the need for increased awareness in other species.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Small Animal Clinic > Small Animal Clinic, Internal Medicine

UniBE Contributor:

Major, Andrea; Schweighauser, Ariane and Francey, Thierry

Subjects:

600 Technology > 610 Medicine & health
600 Technology > 630 Agriculture

ISSN:

1661-7827

Publisher:

Molecular Diversity Preservation International MDPI

Language:

English

Submitter:

Thierry Francey-Spicher

Date Deposited:

14 Oct 2014 16:32

Last Modified:

13 Dec 2014 13:36

Publisher DOI:

10.3390/ijerph110707242

PubMed ID:

25032740

BORIS DOI:

10.7892/boris.59202

URI:

https://boris.unibe.ch/id/eprint/59202

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