Update on skin allergy.

Schlapbach, Christoph; Simon, Dagmar (2014). Update on skin allergy. Allergy, 69(12), pp. 1571-1581. Wiley-Blackwell 10.1111/all.12529

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Skin diseases with an allergic background such as atopic dermatitis, allergic contact dermatitis, and urticaria are very common. Moreover, diseases arising from a dysfunction of immune cells and/or their products often manifest with skin symptoms. This review aims to summarize recently published articles in order to highlight novel research findings, clinical trial results, and current guidelines on disease management. In recent years, an immense progress has been made in understanding the link between skin barrier dysfunction and allergic sensitization initiating the atopic march. In consequence, new strategies for treatment and prevention have been developed. Novel pathogenic insights, for example, into urticaria, angioedema, mastocytosis, led to the development of new therapeutic approaches and their implementation in daily patient care. By understanding distinct pathomechanisms, for example, the role of IL-1, novel entities such as autoinflammatory diseases have been described. Considerable effort has been made to improve and harmonize patient management as documented in several guidelines and position papers.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology

UniBE Contributor:

Schlapbach, Christoph and Simon, Dagmar

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0105-4538

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Monika Schenk

Date Deposited:

15 Apr 2015 15:22

Last Modified:

19 Oct 2015 11:29

Publisher DOI:

10.1111/all.12529

PubMed ID:

25283085

Uncontrolled Keywords:

atopic dermatitis; autoinflammatory diseases; drug hypersensitivity; mastocytosis; urticaria

BORIS DOI:

10.7892/boris.60521

URI:

https://boris.unibe.ch/id/eprint/60521

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