Histological review of skin cancers in African Albinos: a 10-year retrospective review.

Kiprono, Samson Kimaiyo; Chaula, Baraka Michael; Beltraminelli, Helmut (2014). Histological review of skin cancers in African Albinos: a 10-year retrospective review. BMC cancer, 14(157), p. 157. BioMed Central 10.1186/1471-2407-14-157

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BACKGROUND Skin cancer is rare among Africans and albinism is an established risk for skin cancer in this population. Ultraviolet radiation is highest at the equator and African albinos living close to the equator have the highest risk of developing skin cancers. METHODS This was a retrospective study that involved histological review of all specimens with skin cancers from African albinos submitted to The Regional Dermatology Training Center in Moshi, Tanzania from 2002 to 2011. RESULTS A total of 134 biopsies from 86 patients with a male to female ratio of 1:1 were reviewed. Head and neck was the commonest (n = 75, 56.0%) site affected by skin cancers. Squamous cell carcinoma (SCC) was more common than basal cell carcinoma (BCC) with a ratio of 1.2:1. Only one Acral lentiginous melanoma was reported. Majority (55.6%) of SCC were well differentiated while nodular BCC (75%) was the most common type of BCC. CONCLUSIONS Squamous cell carcinoma is more common than basal cell carcinoma in African albinos.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology

UniBE Contributor:

Beltraminelli, Helmut

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1471-2407

Publisher:

BioMed Central

Language:

English

Submitter:

Monika Schenk

Date Deposited:

15 Apr 2015 09:01

Last Modified:

26 Jun 2016 01:56

Publisher DOI:

10.1186/1471-2407-14-157

PubMed ID:

24597988

BORIS DOI:

10.7892/boris.60538

URI:

https://boris.unibe.ch/id/eprint/60538

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