Expression of the nociceptin precursor and nociceptin receptor is modulated in cancer and septic patients

Stamer, U M; Book, M; Comos, C; Zhang, L; Nauck, F; Stüber, F (2011). Expression of the nociceptin precursor and nociceptin receptor is modulated in cancer and septic patients. British journal of anaesthesia, 106(4), pp. 566-72. Oxford: Oxford University Press 10.1093/bja/aer007

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A role of nociceptin and its receptor (NOP) in pain and immune function has been suggested. The hypothesis was that mRNA expression of NOP and the nociceptin precursor pre-pronociceptin (pN/OFQ) in peripheral blood cells differs in end-stage cancer patients suffering from chronic pain and septic intensive care unit (ICU) patients compared with healthy controls.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic and Policlinic for Anaesthesiology and Pain Therapy

UniBE Contributor:

Stamer, Ulrike; Book, Malte and Stüber, Frank

ISSN:

0007-0912

Publisher:

Oxford University Press

Language:

English

Submitter:

Jeannie Wurz

Date Deposited:

04 Oct 2013 14:19

Last Modified:

27 Apr 2018 09:31

Publisher DOI:

10.1093/bja/aer007

PubMed ID:

21324928

Web of Science ID:

000288566800018

BORIS DOI:

10.7892/boris.6056

URI:

https://boris.unibe.ch/id/eprint/6056 (FactScience: 210949)

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