Image registration for triggered and non-triggered DTI of the human kidney: Reduced variability of diffusion parameter estimation

Seif, Maryam; Lu, Huanxiang; Boesch, Chris; Reyes, Mauricio; Vermathen, Peter (2015). Image registration for triggered and non-triggered DTI of the human kidney: Reduced variability of diffusion parameter estimation. Journal of magnetic resonance imaging, 41(5), pp. 1228-1235. Departments of Clinical Research and Radiology, University of Bern, Bern, Switzerland.: Wiley Interscience 10.1002/jmri.24671

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BACKGROUND: To investigate if non-rigid image-registration reduces motion artifacts in triggered and non-triggered diffusion tensor imaging (DTI) of native kidneys. A secondary aim was to determine, if improvements through registration allow for omitting respiratory-triggering. METHODS: Twenty volunteers underwent coronal DTI of the kidneys with nine b-values (10-700 s/mm2 ) at 3 Tesla. Image-registration was performed using a multimodal nonrigid registration algorithm. Data processing yielded the apparent diffusion coefficient (ADC), the contribution of perfusion (FP ), and the fractional anisotropy (FA). For comparison of the data stability, the root mean square error (RMSE) of the fitting and the standard deviations within the regions of interest (SDROI ) were evaluated. RESULTS: RMSEs decreased significantly after registration for triggered and also for non-triggered scans (P < 0.05). SDROI for ADC, FA, and FP were significantly lower after registration in both medulla and cortex of triggered scans (P < 0.01). Similarly the SDROI of FA and FP decreased significantly in non-triggered scans after registration (P < 0.05). RMSEs were significantly lower in triggered than in non-triggered scans, both with and without registration (P < 0.05). CONCLUSION: Respiratory motion correction by registration of individual echo-planar images leads to clearly reduced signal variations in renal DTI for both triggered and particularly non-triggered scans. Secondarily, the results suggest that respiratory-triggering still seems advantageous.J. Magn. Reson. Imaging 2014. (c) 2014 Wiley Periodicals, Inc.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology > DCR Magnetic Resonance Spectroscopy and Methodology (AMSM)
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute for Surgical Technology & Biomechanics ISTB
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Forschungsbereich Pavillon 52 > Abt. Magnetresonanz-Spektroskopie und Methodologie, AMSM

UniBE Contributor:

Seif, Maryam; Lu, Huanxiang; Boesch, Christoph Hans; Reyes, Mauricio and Vermathen, Peter

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health
200 Religion
000 Computer science, knowledge & systems
600 Technology

ISSN:

1053-1807

Publisher:

Wiley Interscience

Language:

English

Submitter:

Mauricio Antonio Reyes Aguirre

Date Deposited:

16 Jan 2015 08:50

Last Modified:

31 Mar 2016 14:59

Publisher DOI:

10.1002/jmri.24671

PubMed ID:

24962556

Uncontrolled Keywords:

DTI, image registration, kidney, respiratory triggering

BORIS DOI:

10.7892/boris.60998

URI:

https://boris.unibe.ch/id/eprint/60998

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