Doramectin-Intoxikation bei drei Katzenwelpen

Nentwig, Alice; Oevermann, Anna; Burgener, Iwan (2014). Doramectin-Intoxikation bei drei Katzenwelpen. Schweizer Archiv für Tierheilkunde, 156(4), pp. 179-183. Huber 10.1024/0036-7281/a000573

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This case report describes 3 kittens with suspected doramectin toxicity. In a litter of 7 kittens treated with doramectin, 3 developed neurological symptoms. One kitten showed mild apathy and tremors, while a second one additionally presented behavioral changes and seizures that had to be treated with diazepam. Both kittens recovered completely. A third kitten was presented to us in coma 3 days following Treatment with doramectin. Subsequently, this kitten developed behavioral changes such as aggression, hyperesthesia, tremors, and seizures and died 36 hours after presentation. Histopathologic examination of the brain showed cytotoxic edema and polioencephalomalacia. The doramectin dosage of the deceased kitten was 380 μg/kg.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > NeuroCenter
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Small Animal Clinic > Small Animal Clinic, Internal Medicine
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Experimental Clinical Research
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH)

UniBE Contributor:

Nentwig, Alice; Oevermann, Anna and Burgener, Iwan

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0036-7281

Publisher:

Huber

Language:

German

Submitter:

Alice Nentwig

Date Deposited:

13 Jan 2015 13:45

Last Modified:

15 Oct 2015 09:07

Publisher DOI:

10.1024/0036-7281/a000573

PubMed ID:

24686818

BORIS DOI:

10.7892/boris.61522

URI:

https://boris.unibe.ch/id/eprint/61522

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