Effect of a Tibetan herbal mixture on microvascular endothelial function, heart rate variability and biomarkers of inflammation, clotting and coagulation

Schäfer, Daniela; Lambrecht, Julia; Radtke, Thomas; Wilhelm, Matthias; Saner, Hugo (2014). Effect of a Tibetan herbal mixture on microvascular endothelial function, heart rate variability and biomarkers of inflammation, clotting and coagulation. European journal of preventive cardiology, 22(8), pp. 1043-1045. SAGE Publications 10.1177/2047487314544985

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In this 6-week prospective, randomized, placebo-controlled and double-blind study, we investigated the effects of a natural herbal remedy based on a recipe from Tibet (Padma® 28), on microvascular endothelial function, heart rate variability and biomarkers of inflammation, clotting and coagulation in 80 coronary artery disease (CAD) patients (age 66 ± 8 years) on guideline-based medication for secondary prevention. We found no significant effects of Padma 28 and conclude that the addition of Padma 28 to guideline-based secondary prevention treatment of CAD did not lead to significant effects on important surrogate markers in elderly male CAD patients.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Schäfer, Daniela; Radtke, Thomas; Wilhelm, Matthias and Saner, Hugo

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2047-4873

Publisher:

SAGE Publications

Language:

English

Submitter:

David Herzig

Date Deposited:

23 Jan 2015 16:08

Last Modified:

15 Oct 2017 13:01

Publisher DOI:

10.1177/2047487314544985

PubMed ID:

25208904

Uncontrolled Keywords:

Padma 28, coronary artery disease, microvascular endothelial function, EndoPat, autonomic nervous tone, biomarkers

BORIS DOI:

10.7892/boris.61871

URI:

https://boris.unibe.ch/id/eprint/61871

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