Malignant nail tumors

Haneke, Eckart (2014). Malignant nail tumors. Hautarzt, 65(4), pp. 312-320. Springer-Medizin-Verlag 10.1007/s00105-013-2705-z

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Because of the large number of different tissues making up the distal phalanx of fingers and toes, a large variety of malignant tumors can be found in and around the nail apparatus. Bowen disease is probably the most frequent nail malignancy. It is usually seen as a verrucous plaque of the nail fold and nail bed in persons above the age of 40 years. It slowly grows over a period of years or even decades before degenerating to an invasive squamous cell carcinoma. The latter may also occur primarily often as a weeping onycholysis. The next most frequent nail malignancy is ungual melanoma. Those arising from the matrix are usually pigmented and often start with a longitudinal melanonychia whereas those originating from the nail bed remain amelanotic, are often nodular and mistaken for an ingrown nail in an elderly person. The treatment of choice for in situ and early invasive subungual melanomas is generous extirpation of the nail apparatus whereas distal amputation is only indicated for advanced melanomas. In addition to these frequent nail malignancies, nail-specific carcinomas, malignant vascular and osseous tumors, other sarcomas, nail involvement in malignant systemic disorders and metastases may occur. In most cases, they cannot be diagnosed accurately on clinical grounds. Therefore, a high degree of suspicion is necessary in all isolated or single-digit proliferations that do not respond to conservative treatment.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology

UniBE Contributor:

Haneke, Eckart

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0017-8470

Publisher:

Springer-Medizin-Verlag

Language:

German

Submitter:

Monika Schenk

Date Deposited:

16 Apr 2015 10:58

Last Modified:

19 Oct 2015 11:29

Publisher DOI:

10.1007/s00105-013-2705-z

PubMed ID:

24718507

BORIS DOI:

10.7892/boris.61996

URI:

https://boris.unibe.ch/id/eprint/61996

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