Electrodiagnostic evaluation in feline hypertrophic muscular dystrophy

Howard, J.; Jaggy, A.; Busato, A.; Gaschen, F. (2004). Electrodiagnostic evaluation in feline hypertrophic muscular dystrophy. Veterinary journal, 1168(1), pp. 87-92. Elsevier 10.1016/S1090-0233(03)00080-7

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Standard needle electromyography (EMG) of 56 muscles and nerve conduction velocities (NCV) of the ulnar and common peroneal nerves were investigated in each of six cats affected with hypertrophic feline muscular dystrophy, 10 related heterozygote carriers and 10 normal cats. The EMG findings were considered normal in carrier and control cats, and consisted of 33% normal readings, 22% myotonic discharges, 18% fibrillation potentials, 11% prolonged insertional potentials, 10% complex repetitive discharges and 6% positive sharp waves in affected cats. Muscles of the proximal limbs were most frequently affected. No differences in NCV were found between the three cat groups. It was concluded that dystrophin-deficient dystrophic cats have widespread and frequent EMG changes, predominantly myotonic discharges and fibrillation potentials, which are most pronounced in the proximal appendicular muscles.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Small Animal Clinic
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > DKV - Clinical Neurology
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Small Animal Clinic > Small Animal Clinic, Internal Medicine
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Institute of Genetics

UniBE Contributor:

Howard, Judith; Jaggy, André and Busato, André

Subjects:

600 Technology > 630 Agriculture

ISSN:

1090-0233

Publisher:

Elsevier

Language:

English

Submitter:

Judith Howard

Date Deposited:

29 Jan 2015 11:29

Last Modified:

04 Feb 2015 04:16

Publisher DOI:

10.1016/S1090-0233(03)00080-7

PubMed ID:

15158213

BORIS DOI:

10.7892/boris.62281

URI:

https://boris.unibe.ch/id/eprint/62281

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