Computed Ultrasound Tomography in Echo mode (CUTE) of speed of sound for diagnosis and for aberration correction in pulse-echo sonography

Jaeger, Michael; Held, Kai Gerrit; Preisser, Stefan; Peeters, Sara Elisa; Grünig, Michael; Frenz, Martin (March 2014). Computed Ultrasound Tomography in Echo mode (CUTE) of speed of sound for diagnosis and for aberration correction in pulse-echo sonography. Proceedings of SPIE - International Society for Optical Engineering, 9040, 90400A. SPIE 10.1117/12.2042993

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Sound speed as a diagnostic marker for various diseases of human tissue has been of interest for a while. Up to now, mostly transmission ultrasound computed tomography (UCT) was able to detect spatially resolved sound speed, and its promise as a diagnostic tool has been demonstrated. However, UCT is limited to acoustically transparent samples such as the breast. We present a novel technique where spatially resolved detection of sound speed can be achieved using conventional pulse-echo equipment in reflection mode. For this purpose, pulse-echo images are acquired under various transmit beam directions and a two-dimensional map of the sound speed is reconstructed from the changing phase of local echoes using a direct reconstruction method. Phantom results demonstrate that a high spatial resolution (1 mm) and contrast (0.5 % of average sound speed) can be achieved suitable for diagnostic purposes. In comparison to previous reflection-mode based methods, CUTE works also in a situation with only diffuse echoes, and its direct reconstruction algorithm enables real-time application. This makes it suitable as an addition to conventional clinical ultrasound where it has the potential to benefit diagnosis in a multimodal approach. In addition, knowledge of the spatial distribution of sound speed allows full aberration correction and thus improved spatial resolution and contrast of conventional B-mode ultrasound. © (2014) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.

Item Type:

Conference or Workshop Item (Paper)


08 Faculty of Science > Institute of Applied Physics

UniBE Contributor:

Jaeger, Michael, Held, Kai Gerrit, Preisser, Stefan, Peeters, Sara Elisa, Grünig, Michael, Frenz, Martin


600 Technology > 620 Engineering








Martin Frenz-Lips

Date Deposited:

05 Feb 2015 11:48

Last Modified:

05 Dec 2022 14:39

Publisher DOI:



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