Vision impairment at diagnosis of cancer - choroidal metastasis

Jegerlehner, Sabrina; Rothenbühler, Simon Paul; Pabst, Thomas (2014). Vision impairment at diagnosis of cancer - choroidal metastasis. Praxis - schweizerische Rundschau für Medizin, 103(11), pp. 641-647. Huber 10.1024/1661-8157/a001671

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Choroidal metastasis represents the most common type of intraocular malignancy and preferably involves the posterior uveal tract. Breast and lung cancer - known or so far undiagnosed - are most frequently identified as the underlying tumor disease. The majority of patients diagnosed with uveal metastasis have additional metastatic manifestations elsewhere, so re-staging before treatment is recommended. The importance of a multidisciplinary approach is obvious. Early diagnosis and timely initiation of treatment are mandatory in case of vision-threatening situations. External beam radiation remains the therapy of choice. Overall survival of patients with uveal metastasis is limited, averaging six to twelve months. The other eye is frequently enough affected as well, justifying regular ophthalmologic follow-up during the further course of the disease.

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