Laboratory diagnosis of ruminant abortion in Europe.

Borel, Nicole; Frey, Caroline; Gottstein, Bruno; Hilbe, Monika; Pospischil, Andreas; Franzoso, Francesca D; Waldvogel, Andreas (2014). Laboratory diagnosis of ruminant abortion in Europe. Veterinary journal, 200(2), pp. 218-229. Elsevier 10.1016/j.tvjl.2014.03.015

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Abortion in ruminants is a major cause of economic loss worldwide, and the management and control of outbreaks is important in limiting their spread, and in preventing zoonotic infections. Given that rapid and accurate laboratory diagnosis is central to controlling abortion outbreaks, the submission of tissue samples to laboratories offering the most appropriate tests is essential. Direct antigen and/or DNA detection methods are the currently preferred methods of reaching an aetiological diagnosis, and ideally these results are confirmed by the demonstration of corresponding macroscopic and/or histopathological lesions in the fetus and/or the placenta. However, the costs of laboratory examinations may be considerable and, even under optimal conditions, the percentage of aetiological diagnoses reached can be relatively low. This review focuses on the most commonly occurring and important abortifacient pathogens of ruminant species in Europe highlighting their epizootic and zoonotic potential. The performance characteristics of the various diagnostic methods used, including their specific advantages and limitations, are discussed.

Item Type:

Journal Article (Review Article)


05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Parasitology
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)

UniBE Contributor:

Frey, Caroline and Gottstein, Bruno


500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health
600 Technology > 630 Agriculture








Bruno Gottstein

Date Deposited:

17 Feb 2015 15:06

Last Modified:

19 Oct 2015 10:37

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

Abortion, Diagnosis, Europe, Infectious, Ruminant, Zoonotic




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