Angiomatous kaposi sarcoma: a variant that mimics hemangiomas.

Yang, Sara Hsin-Yi; LeBoit, Philip E (2014). Angiomatous kaposi sarcoma: a variant that mimics hemangiomas. American journal of dermatopathology, 36(3), pp. 229-237. Lippincott Williams & Wilkins 10.1097/DAD.0b013e3182996ccd

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We describe 14 cases of angiomatous Kaposi sarcoma (KS), a distinct histological variant of KS first mentioned by Gottlieb and Ackerman in 1988 that can easily be mistaken for a hemangioma. Intriguingly, this variant of KS has not attracted much attention and has not been studied in detail. Immunohistochemistry showed prominent staining of podoplanin (D2-40) of the neoplastic vasculature but not the preexisting vessels, suggesting lymphatic differentiation, despite the erythrocyte-filled round lumens. To test whether D2-40 staining of round vessels with erythrocytes was distinctive, we stained sinusoidal hemangiomas and cellular angiolipomas, both of which have these structures. In contrast to angiomatous KS, the vessels in both entities were podoplanin (D2-40) negative. The finding of round erythrocyte-filled vessels with podoplanin (D2-40) positivity may be distinctive for this form of KS.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Yang, Sara Hsin-Yi

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

0193-1091

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Doris Haefelin

Date Deposited:

23 Feb 2015 14:30

Last Modified:

01 Apr 2015 02:30

Publisher DOI:

10.1097/DAD.0b013e3182996ccd

PubMed ID:

24067801

BORIS DOI:

10.7892/boris.63615

URI:

https://boris.unibe.ch/id/eprint/63615

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