Erdös, Gabor; Basciani, Reto Marco; Eberle Schnüriger, Barbara (2014). Etomidate - a review of robust evidence for its use in various clinical scenarios. Acta anaesthesiologica Scandinavica, 58(4), pp. 380-389. Wiley-Blackwell 10.1111/aas.12289
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Etomidate is an intravenous hypnotic with a favourable clinical profile in haemodynamic high-risk scenarios. Currently, there is an active debate about the clinical significance of the drug's side effects and its overall risk-benefit ratio. Etomidate-induced transient adrenocortical suppression is well documented and has been associated with increased mortality in sepsis. In surgical patients at risk of hypotensive complications, however, a review of current literature provides no robust evidence to contraindicate a single-bolus etomidate induction. Large randomised controlled trials as well as additional observational data are required to compare safety of etomidate and its alternatives.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic and Policlinic for Anaesthesiology and Pain Therapy |
UniBE Contributor: |
Erdoes, Gabor (A), Basciani, Reto Marco, Eberle Schnüriger, Barbara |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0001-5172 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Jeannie Wurz |
Date Deposited: |
23 Feb 2015 16:48 |
Last Modified: |
29 Mar 2023 23:34 |
Publisher DOI: |
10.1111/aas.12289 |
PubMed ID: |
24588359 |
BORIS DOI: |
10.7892/boris.63828 |
URI: |
https://boris.unibe.ch/id/eprint/63828 |
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