Electrical carotid baroreceptor stimulation

Schmidli, Jürg; von Allmen, Regula; Mohaupt, Markus (2014). Electrical carotid baroreceptor stimulation. Wiener medizinische Wochenschrift, 164(23-24), pp. 508-514. Springer 10.1007/s10354-014-0329-2

[img] Text
art%3A10.1007%2Fs10354-014-0329-2.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (610kB) | Request a copy

The Barostim neo ™ system is a novel implantable device that activates the carotid baroreflex. It decreases the sympathetic activity and inhibits the renin system, which results in reduced blood pressure and heart rate. In patients with resistant hypertension, electrically activation of the baroreflex leads to an average decrease in systolic blood pressure of 38, 36, 40 and 53 mmHg at 1, 2, 3 and 4 years, respectively. Additionally, cardiac remodelling with reduced left ventricular mass and posterior wall thickness has been observed in long-term studies. In a limited number of patients with heart failure, baroreflex activation therapy leads to a decrease in muscle sympathetic nerve activity and to improved quality of life and functional capacities. The implantation procedure is safe and associated with risks comparable with those of other active implantable devices. Barostim neo is currently available in several European countries.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Nephrology and Hypertension
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiovascular Surgery

UniBE Contributor:

Schmidli, Jürg; von Allmen, Regula and Mohaupt, Markus

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0043-5341

Publisher:

Springer

Language:

English

Submitter:

Sara Baumberger

Date Deposited:

05 Mar 2015 15:59

Last Modified:

27 Oct 2015 11:26

Publisher DOI:

10.1007/s10354-014-0329-2

PubMed ID:

25411011

BORIS DOI:

10.7892/boris.64108

URI:

https://boris.unibe.ch/id/eprint/64108

Actions (login required)

Edit item Edit item
Provide Feedback