Clinical herniation – how to improve differentiation between WFNS grade IV and V

Fung, Christian; Murek, Michael; Z'Graggen, Werner Josef; Ozdoba, Christoph; Beck, Jürgen; Raabe, Andreas (2014). Clinical herniation – how to improve differentiation between WFNS grade IV and V (Unpublished). In: 65. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC). Dresden. 11.-14.05.2014.

Objective: Current data show a favorable outcome after poor grade subarachnoid hemorrhage (SAH) in up to 50% of patients. This limits the use of the WFNS scale for drawing treatment decisions. We therefore analyzed how clinical signs of herniation might improve the existing WFNS grading. Therefore we compared the current WFNS grading and a modified WFNS grading with respect to outcome. Method: We performed a retrospective study including 182 poor grade SAH patients. Patients were graded according to the original WFNS scale and additionally into a modified classification the “WFNS herniation” (WFNSh grade IV: no herniation; grade V clinical signs of herniation). Outcome was compared between these two grading systems with respect to the dichotomized modified Rankin scale after 6 months. Results: The WFNS and WFNSh showed a positive predictive value (PPV) for poor outcome of 74.3% (OR 3.79, 95% confidence interval [CI]=1.94, 7.54) and 85.7% (OR 8.27, 95% CI=3.78, 19.47), respectively. With respect to mortality the PPV was 68.3% (OR 3.9, 95% CI=2.01, 7.69) for the WFNS grade V and 77.9% (OR 6.22, 95% CI=3.07, 13.14) for the WFNSh grade V. Conclusions: Using positive clinical signs of herniation instead of “no response to pain stimuli” (motor Glasgow Coma Scale Score) can improve WFNS V grading. Using this modification, prediction of poor outcome or death improves.

Item Type:

Conference or Workshop Item (Poster)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology

UniBE Contributor:

Fung, Christian; Murek, Michael; Z'Graggen, Werner Josef; Ozdoba, Christoph; Beck, Jürgen and Raabe, Andreas

Subjects:

600 Technology > 610 Medicine & health

Language:

German

Submitter:

Nicole Söll

Date Deposited:

13 Mar 2015 12:52

Last Modified:

13 Mar 2015 12:52

URI:

https://boris.unibe.ch/id/eprint/64607

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