Senile scleral plaques imaged with enhanced depth optical coherence tomography

Beck, Marco; Schlatter, Bettina; Wolf, Sebastian; Zinkernagel, Martin (2015). Senile scleral plaques imaged with enhanced depth optical coherence tomography. Acta ophthalmologica, 93(3), e188-e192. Blackwell Munksgaard 10.1111/aos.12547

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PURPOSE Senile scleral plaques (SSP) are sharply demarcated greyish areas located just anterior to the insertions of the horizontal rectus muscles and thus are frequently encountered during transscleral intravitreal injections. The aim of this study was to characterize SSP using enhanced depth imaging spectral domain anterior segment optical coherence tomography (OCT) in a cohort of patients attending intravitreal injection clinics. METHODS Prospective cross-sectional study of 380 patients attending the clinic for intravitreal injections at the Department of Ophthalmology at the Bern University Hospital. Thirty-two patients with SSP were identified and the anatomical features were assessed using anterior segment OCT. RESULTS In our patient cohort, we found a SSP prevalence of 8.2%. Senile scleral plaques were easily identifiable using anterior segment OCT and were found at the insertion sites of the horizontal recti muscles. The mean horizontal diameter was 2.2 mm (±760 μm SD), the mean vertical diameter was 3.3 mm (±144 μm SD), and the average surface area was 5.3 mm(2) (±0.4 mm(2) SD). The mean senile scleral plaque thickness was 0.6 mm (±149 μm SD). The mean distance from the limbus was 2.24 mm for nasally located SSP and 3.22 mm for temporally located SSP. CONCLUSION SSP are frequently encountered during intravitreal injections as they are located just anterior to the insertion sites of the horizontal recti muscles. Because the scleral stroma is rarefied and due to calcifications within SSP, these areas should be avoided when performing multiple intravitreal injections as this may result in rupture of the sclera.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology
04 Faculty of Medicine > Medical Education > Institute for Medical Education > Curriculum Coordination & Students' Office (STPL)

UniBE Contributor:

Beck, Marco; Wolf, Sebastian and Zinkernagel, Martin


600 Technology > 610 Medicine & health
500 Science




Blackwell Munksgaard




Sebastian Wolf

Date Deposited:

16 Mar 2015 12:09

Last Modified:

17 Feb 2016 16:13

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

anterior segment optical coherence tomography; sclera; senile scleral plaques




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