Spectral-domain optical coherence tomography findings after severe exogenous endophthalmitis

Zinkernagel, Martin; Dysli, Chantal-Simone; Wolf, Sebastian; Ebneter, Andreas (2014). Spectral-domain optical coherence tomography findings after severe exogenous endophthalmitis. Ocular immunology and inflammation, 22(6), pp. 439-443. Informa Healthcare 10.3109/09273948.2014.949780

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PURPOSE To report outcomes and assess structural changes in the retina in patients with severe endophthalmitis. METHODS Retrospective, nonrandomized, interventional case series at a tertiary referral centre. Spectral domain optical coherence tomography (OCT) images of both eyes were acquired at least 5 months after pars plana vitrectomy. OCT images were analyzed using retinal layer segmentation. RESULTS Nine patients (46-80 years of age) were included in this study. Average ETDRS visual acuity before treatment was 23 letters and improved to 74 letters. In our cohort we did not find a generalized reduction of retinal layers using automated layer segmentation. CONCLUSION Our findings suggest that prompt treatment of severe endophthalmitis with intravitreal antibiotics followed by pars plana vitrectomy may lead to excellent visual outcomes with minimal damage to the retinal architecture.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

UniBE Contributor:

Zinkernagel, Martin; Dysli, Chantal-Simone; Wolf, Sebastian and Ebneter, Andreas


600 Technology > 610 Medicine & health
500 Science




Informa Healthcare




Sebastian Wolf

Date Deposited:

16 Mar 2015 12:22

Last Modified:

05 Nov 2015 09:35

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

Endophthalmitis, OCT, retina segmentation



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