Pulmonary aspergilloma: A rare differential diagnosis to lung cancer after positive FDG PET scan

Spycher, Franziska; Kocher, Gregor J.; Gugger, Mathias; Geiser, Thomas; Ott, Sebastian Robert (2014). Pulmonary aspergilloma: A rare differential diagnosis to lung cancer after positive FDG PET scan. Respiratory Medicine Case Reports, 12, pp. 1-3. Elsevier 10.1016/j.rmcr.2014.02.003

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Early diagnosis and treatment of lung cancer, one of the leading causes of cancer-related death, is important to improve morbidity and mortality. Therefore any suspect solitary pulmonary nodule should prompt the pursuit for a definitive histological diagnosis. We describe the case of a 55-years-old male ex-smoker, who was admitted to our hospital due to recurrent hemoptysis and dry cough. A CT scan showed an irregular nodule of increasing size (28 mm in diameter) in the left lower lobe (LLL). A whole body PET-CT scan (643 MBq F-18 FDG i.v.) was performed and confirmed an avid FDG uptake of the nodule in the LLL, highly suspicious of lung cancer, without any evidence of lymphogenic or hematogenic metastasis. Bronchoscopy was not diagnostic and due to severe adhesions after prior chest trauma and the central location of the nodule, a lobectomy of the LLL was performed. Surprisingly, histology showed a simple aspergilloma located in a circumscribed bronchiectasis with no evidence of malignancy. This is a report of an informative example of an aspergilloma, which presented with symptoms and radiological features of malignant lung cancer.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Pneumology

UniBE Contributor:

Spycher, Franziska; Geiser, Thomas and Ott, Sebastian Robert

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2213-0071

Publisher:

Elsevier

Language:

English

Submitter:

Rahel Holderegger

Date Deposited:

18 Mar 2015 11:32

Last Modified:

19 Mar 2015 22:32

Publisher DOI:

10.1016/j.rmcr.2014.02.003

BORIS DOI:

10.7892/boris.64941

URI:

https://boris.unibe.ch/id/eprint/64941

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