Implementation of a mandatory donor RHD screening in Switzerland

Crottet, Sofia Lejon; Henny, Christine; Meyer, Stefan; Still, Franziska; Stolz, Martin; Gottschalk, Jochen; Neuenschwander, Kathrin; Mansouri Taleghani, Behrouz; Gowland, Peter; Frey, Beat M; Fontana, Stefano; Hustinx, Hein; Niederhauser, Christoph; Gassner, Christoph (2014). Implementation of a mandatory donor RHD screening in Switzerland. Transfusion and apheresis science, 50(2), pp. 169-174. Elsevier 10.1016/j.transci.2014.02.011

[img] Text
BM_2014_1-s2 0-S1473050214000512-main.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (233kB) | Request a copy

Starting in 2013, blood donors must be tested at least using: (1) one monoclonal anti-D and one anti-CDE (alternatively full RhCcEe phenotyping), and (2) all RhD negative donors must be tested for RHD exons 5 and 10 plus one further exonic, or intronic RHD specificity, according to the guidelines of the Blood Transfusion Service of the Swiss Red Cross (BTS SRC). In 2012 an adequate stock of RHD screened donors was built. Of all 25,370 RhD negative Swiss donors tested in 2012, 20,015 tested at BTS Berne and 5355 at BTS Zürich, showed 120 (0.47%) RHD positivity. Thirty-seven (0.15%) had to be redefined as RhD positive. Routine molecular RHD screening is reliable, rapid and cost-effective and provides safer RBC units in Switzerland.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Haematology and Central Haematological Laboratory

UniBE Contributor:

Mansouri Taleghani, Behrouz

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1473-0502

Publisher:

Elsevier

Language:

English

Submitter:

Verena Zwahlen

Date Deposited:

26 Mar 2015 11:22

Last Modified:

10 Sep 2017 11:43

Publisher DOI:

10.1016/j.transci.2014.02.011

PubMed ID:

24679597

Uncontrolled Keywords:

Molecular RHD screening, National guidelines Rhesus D

BORIS DOI:

10.7892/boris.66072

URI:

https://boris.unibe.ch/id/eprint/66072

Actions (login required)

Edit item Edit item
Provide Feedback