Regional Radiation Pneumonitis After SIRT of a Subcapsular Liver Metastasis: What is the Effect of Direct Beta Irradiation?

Dobrocky, Tomas; Fürstner, Markus; Klaeser, Bernd; Lopez-Benitez, Ruben; Wälti, Yara Banz; Kara, Levent (2015). Regional Radiation Pneumonitis After SIRT of a Subcapsular Liver Metastasis: What is the Effect of Direct Beta Irradiation? Cardiovascular and interventional radiology, 38(4), pp. 1025-1030. Springer 10.1007/s00270-014-1015-x

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We herein present a patient undergoing selective internal radiation therapy with an almost normal lung shunt fraction of 11.5 %, developing histologically proven radiation pneumonitis. Due to a predominance of pulmonary consolidations in the right lower lung and its proximity to a large liver metastases located in the dome of the right liver lobe a Monte Carlo simulation was performed to estimate the effect of direct irradiation of the lung parenchyma. According to our calculations direct irradiation seems negligible and RP is almost exclusively due to ectopic draining of radioactive spheres.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Clinic of Nuclear Medicine
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology

UniBE Contributor:

Dobrocky, Tomas; Fürstner, Markus; Klaeser, Bernd and Kara, Levent

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0174-1551

Publisher:

Springer

Language:

English

Submitter:

Aisha Stefania Mzinga

Date Deposited:

09 Apr 2015 15:59

Last Modified:

24 Feb 2016 08:20

Publisher DOI:

10.1007/s00270-014-1015-x

PubMed ID:

25373797

BORIS DOI:

10.7892/boris.66090

URI:

https://boris.unibe.ch/id/eprint/66090

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