Fluri, Simon; Kaczala, Gregor W; Leibundgut, Kurt; Alberio, Lorenzo (2010). Chickenpox is not always benign: postvaricella purpura fulminans requires prompt and aggressive treatment. Pediatric emergency care, 26(12), pp. 932-4. Baltimore, Md.: Williams & Wilkins 10.1097/PEC.0b013e3181fe91cd
Full text not available from this repository. (Request a copy)We present 2 patients, who were admitted owing to rapidly progressing purpuric lesions due to postvaricella purpura fulminans, a coagulopathy leading to life- or limb-threatening thrombosis caused by a severe transient autoimmune protein S deficiency. Laboratory results were being consistent with disseminated intravascular coagulation secondary to protein S deficiency; treatment with fresh frozen plasma, intravenous immunoglobulins, and prednisone was started. In our experience, a prompt therapy may limit the course and the extent of the disease. We present a review of the topic with supporting literature for the therapeutic options. Therefore, we should be reminded that purpura fulminans is a rare but severe complication of chickenpox, which demands quick action.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine 04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Haematology and Central Haematological Laboratory |
UniBE Contributor: |
Fluri, Simon, Kaczala, Gregor Wladyslaw Eusebius, Leibundgut, Kurt, Alberio, Lorenzo |
ISSN: |
0749-5161 |
Publisher: |
Williams & Wilkins |
Language: |
English |
Submitter: |
Anette van Dorland |
Date Deposited: |
04 Oct 2013 14:08 |
Last Modified: |
05 Dec 2022 14:00 |
Publisher DOI: |
10.1097/PEC.0b013e3181fe91cd |
PubMed ID: |
21131808 |
Web of Science ID: |
000284943800014 |
URI: |
https://boris.unibe.ch/id/eprint/662 (FactScience: 200333) |
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