Zürcher-Hürlimann, Elian; grosse Holtforth, Martin; Hermann, Ernst (2014). Long-Term Effects of the Treatment of Depressive Female Inpatients in a Naturalistic Study: Is Early Improvement a Valid Predictor of Outcome? Depression Research and Treatment, 2014(780237), pp. 1-8. Hindawi Publishing Corporation 10.1155/2014/780237
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Objectives: To examine the predictive value of early improvement for short- and long-term outcome in the treatment of depressive female inpatients and to explore the influence of comorbid disorders (CD). Methods: Archival data of a naturalistic sample of 277 female inpatients diagnosed with a depressive disorder was analyzed assessing the BDI at baseline, after 20 days and 30 days, posttreatment, and after 3 to 6 months at follow-up. Early improvement, defined as a decrease in the BDI score of at least 30% after 20 and after 30 days, and CD were analyzed using binary logistic regression. Results: Both early improvement definitions were predictive of remission at posttreatment. Early improvement after 30 days showed a sustained treatment effect in the follow-up phase, whereas early improvement after 20 days failed to show a persistent effect regarding remission at follow-up. CD were not significantly related neither at posttreatment nor at follow-up. At no time point CD moderated the prediction by early improvement. Conclusions: We show that early improvement is a valid predictor for short-term remission and at follow-up in an inpatient setting. CD did not predict outcome. Further studies are needed to identify patient subgroups amenable to more tailored treatments.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine 07 Faculty of Human Sciences > Institute of Psychology > Clinical Psychology and Psychotherapy 07 Faculty of Human Sciences > Institute of Psychology |
UniBE Contributor: |
Zürcher-Hürlimann, Elian, Grosse Holtforth, Martin |
Subjects: |
600 Technology > 610 Medicine & health 100 Philosophy > 150 Psychology |
ISSN: |
2090-1321 |
Publisher: |
Hindawi Publishing Corporation |
Language: |
English |
Submitter: |
Adriana Biaggi |
Date Deposited: |
07 Apr 2015 14:41 |
Last Modified: |
30 Mar 2023 16:18 |
Publisher DOI: |
10.1155/2014/780237 |
BORIS DOI: |
10.7892/boris.66524 |
URI: |
https://boris.unibe.ch/id/eprint/66524 |
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