Review of recent results using computational fluid dynamics simulations in patients receiving mechanical assist devices for end-stage heart failure

Farag, Mina Berty; Karmonik, Christof; Rengier, Fabian; Loebe, Matthias; Karck, Matthias; von Tengg-Kobligk, Hendrik; Ruhparwar, Arjang; Partovi, Sasan (2014). Review of recent results using computational fluid dynamics simulations in patients receiving mechanical assist devices for end-stage heart failure. Methodist DeBakey cardiovascular journal, 10(3), pp. 185-189. Methodist DeBakey Heart & Vascular Center 10.14797/mdcj-10-3-185

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Many end-stage heart failure patients are not eligible to undergo heart transplantation due to organ shortage, and even those under consideration for transplantation might suffer long waiting periods. A better understanding of the hemodynamic impact of left ventricular assist devices (LVAD) on the cardiovascular system is therefore of great interest. Computational fluid dynamics (CFD) simulations give the opportunity to study the hemodynamics in this patient population using clinical imaging data such as computed tomographic angiography. This article reviews a recent study series involving patients with pulsatile and constant-flow LVAD devices in which CFD simulations were used to qualitatively and quantitatively assess blood flow dynamics in the thoracic aorta, demonstrating its potential to enhance the information available from medical imaging.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology

UniBE Contributor:

von Tengg-Kobligk, Hendrik

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1947-6108

Publisher:

Methodist DeBakey Heart & Vascular Center

Language:

English

Submitter:

Aisha Stefania Mzinga

Date Deposited:

01 May 2015 15:17

Last Modified:

02 May 2015 06:27

Publisher DOI:

10.14797/mdcj-10-3-185

PubMed ID:

25574347

Uncontrolled Keywords:

computational fluid dynamics, left ventricular assist device, heart failure

BORIS DOI:

10.7892/boris.66780

URI:

https://boris.unibe.ch/id/eprint/66780

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