In vitro study to simulate the intracardiac magnetohydrodynamic effect

Buchenberg, Waltraud B; Mader, Wolfgang; Hoppe, Georg; Lorenz, Ramona; Menza, Marius; Büchert, Martin; Timmer, Jens; Jung, Bernd (2014). In vitro study to simulate the intracardiac magnetohydrodynamic effect. Magnetic resonance in medicine, 74(3), pp. 850-857. Wiley-Liss 10.1002/mrm.25456

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PURPOSE Blood flow causes induced voltages via the magnetohydrodynamic (MHD) effect distorting electrograms (EGMs) made during magnetic resonance imaging. To investigate the MHD effect in this context MHD voltages occurring inside the human heart were simulated in an in vitro model system inside a 1.5 T MR system. METHODS The model was developed to produce MHD signals similar to those produced by intracardiac flow and to acquire them using standard clinical equipment. Additionally, a new approach to estimate MHD distortions on intracardiac electrograms is proposed based on the analytical calculation of the MHD signal from MR phase contrast data. RESULTS The recorded MHD signals were similar in magnitude to intracardiac signals that would be measured by an electrogram of the left ventricle. The dependency of MHD signals on magnetic field strength and electrode separation was well reflected by an analytical model. MHD signals reconstructed from MR flow data were in excellent agreement with the MHD signal measured by clinical equipment. CONCLUSION The in vitro model allows investigation of MHD effects on intracardiac electrograms. A phase contrast MR scan was successfully applied to characterize and estimate the MHD distortion on intracardiac signals allowing correction of these effects. Magn Reson Med, 2014. © 2014 Wiley Periodicals, Inc.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology

UniBE Contributor:

Jung, Bernd

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0740-3194

Publisher:

Wiley-Liss

Language:

English

Submitter:

Aisha Stefania Mzinga

Date Deposited:

01 May 2015 15:05

Last Modified:

26 Jun 2016 02:01

Publisher DOI:

10.1002/mrm.25456

PubMed ID:

25224650

Uncontrolled Keywords:

electrophysiology hemodynamics in vitro model system intracardiac electrograms magnetohydrodynamic effect phase contrast MRI

BORIS DOI:

10.7892/boris.66859

URI:

https://boris.unibe.ch/id/eprint/66859

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