Kamm, Christian Philipp; Mattle, Heinrich P.; Müri, René Martin; Heldner, Mirjam Rachel; Blatter Arifi, Verena; Bartlome, Sandrine; Lüthy, Judith; Imboden, Debora; Pedrazzini, Giovanna Rachele Marilyn; Bohlhalter, Stephan; Hilfiker, Roger; Vanbellingen, Tim (2015). Home-based training to improve manual dexterity in patients with multiple sclerosis: A randomized controlled trial. Multiple sclerosis journal, 21(12), pp. 1546-1556. Sage 10.1177/1352458514565959
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Mult Scler-2015-Kamm-1352458514565959.pdf - Published Version Restricted to registered users only Available under License Publisher holds Copyright. Download (1MB) |
BACKGROUND
Impaired manual dexterity is frequent and disabling in patients with multiple sclerosis (MS), affecting activities of daily living (ADL) and quality of life.
OBJECTIVE
We aimed to evaluate the effectiveness of a standardized, home-based training program to improve manual dexterity and dexterity-related ADL in MS patients.
METHODS
This was a randomized, rater-blinded controlled trial. Thirty-nine MS patients acknowledging impaired manual dexterity and having a pathological Coin Rotation Task (CRT), Nine Hole Peg Test (9HPT) or both were randomized 1:1 into two standardized training programs, the dexterity training program and the theraband training program. Patients trained five days per week in both programs over a period of 4 weeks. Primary outcome measures performed at baseline and after 4 weeks were the CRT, 9HPT and a dexterous-related ADL questionnaire. Secondary outcome measures were the Chedoke Arm and Hand Activity Inventory (CAHAI-8) and the JAMAR test.
RESULTS
The dexterity training program resulted in significant improvements in almost all outcome measures at study end compared with baseline. The theraband training program resulted in mostly non-significant improvements.
CONCLUSION
The home-based dexterity training program significantly improved manual dexterity and dexterity-related ADL in moderately disabled MS patients. Trial Registration NCT01507636.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology |
UniBE Contributor: |
Kamm, Christian Philipp, Mattle, Heinrich, Müri, René Martin, Heldner, Mirjam Rachel, Blatter Arifi, Verena, Pedrazzini, Giovanna Rachele Marilyn, Bohlhalter, Stephan, Vanbellingen, Tim |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1352-4585 |
Publisher: |
Sage |
Language: |
English |
Submitter: |
Valentina Rossetti |
Date Deposited: |
05 May 2015 09:54 |
Last Modified: |
05 Dec 2022 14:46 |
Publisher DOI: |
10.1177/1352458514565959 |
PubMed ID: |
25623246 |
Uncontrolled Keywords: |
Multiple sclerosis; controlled clinical trials; hand function; home-based training program; manual dexterity; manual therapies; randomized |
BORIS DOI: |
10.7892/boris.67943 |
URI: |
https://boris.unibe.ch/id/eprint/67943 |
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