Diffusion-weighted magnetic resonance imaging detects local recurrence after radical prostatectomy: initial experience

Giannarini, Gianluca; Nguyen, Daniel P; Thalmann, George N; Thoeny, Harriet C (2012). Diffusion-weighted magnetic resonance imaging detects local recurrence after radical prostatectomy: initial experience. European urology, 61(3), pp. 616-20. Amsterdam: Elsevier 10.1016/j.eururo.2011.11.030

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Current conventional cross-sectional imaging techniques, such as contrast-enhanced computed tomography and magnetic resonance imaging (MRI), are largely inaccurate in detecting local recurrence after radical prostatectomy. We report on five patients with biochemical recurrence after radical retropubic prostatectomy and pelvic lymph node dissection for whom local recurrence could only be detected with diffusion-weighted (DW) MRI. Prior to DW-MRI, all patients had negative digital rectal examinations, negative or equivocal conventional cross-sectional imaging, and negative bone scans. All suspicious lesions on DW-MRI imaging were histologically proved to be local recurrences of prostate cancer after either transrectal ultrasound-guided or transurethral biopsy. These results should encourage other centres to test our findings.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Urology
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology

UniBE Contributor:

Nguyen, Daniel Truong Phat; Thalmann, George and Thöny, Harriet C.

ISSN:

0302-2838

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:20

Last Modified:

06 Dec 2013 13:27

Publisher DOI:

10.1016/j.eururo.2011.11.030

PubMed ID:

22137601

Web of Science ID:

000300194000043

URI:

https://boris.unibe.ch/id/eprint/6803 (FactScience: 211833)

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