Vapor bubble generation around gold nano-particles and its application to damaging of cells

Kitz, M; Preisser, S; Wetterwald, A; Jaeger, M; Thalmann, G N; Frenz, M (2011). Vapor bubble generation around gold nano-particles and its application to damaging of cells. Biomedical optics express, 2(2), pp. 291-304. Washington, D.C.: Optical Society of America 10.1364/BOE.2.000291

Full text not available from this repository. (Request a copy)

We investigated vapor bubbles generated upon irradiation of gold nanoparticles with nanosecond laser pulses. Bubble formation was studied both with optical and acoustic means on supported single gold nanoparticles and single nanoparticles in suspension. Formation thresholds determined at different wavelengths indicate a bubble formation efficiency increasing with the irradiation wavelength. Vapor bubble generation in Bac-1 cells containing accumulations of the same particles was also investigated at different wavelengths. Similarly, they showed an increasing cell damage efficiency for longer wavelengths. Vapor bubbles generated by single laser pulses were about half the cell size when inducing acute damage.

Item Type:

Journal Article (Original Article)


08 Faculty of Science > Institute of Applied Physics
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Urology

UniBE Contributor:

Kitz, Michael, Preisser, Stefan, Jaeger, Michael, Thalmann, George, Frenz, Martin




Optical Society of America




Factscience Import

Date Deposited:

04 Oct 2013 14:20

Last Modified:

05 Dec 2022 14:05

Publisher DOI:


PubMed ID:


Web of Science ID:


URI: (FactScience: 211837)

Actions (login required)

Edit item Edit item
Provide Feedback