Glucagon-like peptide-1 (GLP-1) receptors are not overexpressed in pancreatic islets from patients with severe hyperinsulinaemic hypoglycaemia following gastric bypass

Reubi, J.C.; Perren, A; Rehmann, R; Waser, B; Christ, E; Callery, M; Goldfine, A B; Patti, M E (2010). Glucagon-like peptide-1 (GLP-1) receptors are not overexpressed in pancreatic islets from patients with severe hyperinsulinaemic hypoglycaemia following gastric bypass. Diabetologia, 53(12), pp. 2641-5. Heidelberg: Springer-Verlag 10.1007/s00125-010-1901-y

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Glucagon-like peptide-1 (GLP-1) receptors are highly overexpressed in benign insulinomas, permitting in vivo tumour visualisation with GLP-1 receptor scanning. The present study sought to evaluate the GLP-1 receptor status in vitro in other pancreatic disorders leading to hyperinsulinaemic hypoglycaemia, specifically after gastric bypass surgery.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition

UniBE Contributor:

Reubi-Kattenbusch, Jean-Claude; Perren, Aurel; Waser, Beatrice and Christ, Emanuel

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

0012-186X

Publisher:

Springer-Verlag

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:08

Last Modified:

23 Oct 2019 03:44

Publisher DOI:

10.1007/s00125-010-1901-y

PubMed ID:

20835917

Web of Science ID:

000284509900023

BORIS DOI:

10.7892/boris.685

URI:

https://boris.unibe.ch/id/eprint/685 (FactScience: 200389)

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