Vonlanthen, David; Leumann, Christian (2003). Hydroxycyclopentanone derivatives from D-Mannose via ring closing metathesis: An improved synthesis of a key intermediate of Tricyclo-DNA. Synthesis - journal of synthetic organic chemistry, 2003(07), pp. 1087-1090. Thieme 10.1055/s-2003-39177
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A large scale, 10 step synthesis of cyclopentanone 1 , starting from the chiral pool compound D-mannose, is described. The synthesis proceeds via a ring closing metathesis reaction as the key step in an overall yield of 23%. Cyclopentanone 1 is a central intermediate for the synthesis of tricyclo-DNA
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) |
UniBE Contributor: |
Vonlanthen, David, Leumann, Christian |
Subjects: |
500 Science > 570 Life sciences; biology 500 Science > 540 Chemistry |
ISSN: |
0039-7881 |
Publisher: |
Thieme |
Language: |
English |
Submitter: |
Christian Leumann |
Date Deposited: |
19 May 2015 10:24 |
Last Modified: |
05 Dec 2022 14:46 |
Publisher DOI: |
10.1055/s-2003-39177 |
Uncontrolled Keywords: |
large-scale synthesis tricyclo-DNA |
BORIS DOI: |
10.7892/boris.68561 |
URI: |
https://boris.unibe.ch/id/eprint/68561 |
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