Olefinic peptide nucleic acid (OPA)

Gautschi, Daniel; Leumann, Christian (2003). Olefinic peptide nucleic acid (OPA). Nucleosides, nucleotides & nucleic acids, 22(5-8), pp. 1211-1213. Taylor & Francis 10.1081/NCN-120022838

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The olefinic peptide nucleic acid analogues (OPA) monomers containing the bases thymine and adenine were synthesised in 11 steps. Fully modified oligomers containing these units were prepared and their pairing properties assessed by means of UV-melting experiments

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Departement of Chemistry and Biochemistry

UniBE Contributor:

Gautschi, Daniel and Leumann, Christian

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 540 Chemistry

ISSN:

1525-7770

Publisher:

Taylor & Francis

Language:

English

Submitter:

Christian Leumann

Date Deposited:

19 May 2015 09:12

Last Modified:

19 May 2015 09:12

Publisher DOI:

10.1081/NCN-120022838

PubMed ID:

14565382

Additional Information:

Notes: Department of Chemistry and Biochemistry, University of Bern, Bern, SwitzerlandFAU - Gautschi, Daniel

Uncontrolled Keywords:

ACID adenine Alkenes analogue analogues base Base Pairing Base Sequence bases chemical synthesis chemistry modified monomers nucleic acid analogues Nucleic Acid Denaturation OLIGODEOXYRIBONUCLEOTIDES oligomers OPA PAIRING PROPERTIES peptide Peptide Nucleic Acids properties Spectrum Analysis,Mass THYMINE

BORIS DOI:

10.7892/boris.68567

URI:

https://boris.unibe.ch/id/eprint/68567

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