New nucleoside analogues for the recognition of pyrimidine-purine inversion sites

Buchini, S.; Leumann, Christian (2003). New nucleoside analogues for the recognition of pyrimidine-purine inversion sites. Nucleosides, nucleotides & nucleic acids, 22(5-8), pp. 1199-1201. Taylor & Francis 10.1081/NCN-120022835

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A new nucleoside designed to enhance triplex stability has been synthesised in 15 steps starting from sugar 2. This pathway contains the sugar derivative 9 which is a useful intermediate for the introduction of other natural and unnatural bases into the 2'-aminoethoxy nucleoside containing scaffold

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Departement of Chemistry and Biochemistry

UniBE Contributor:

Leumann, Christian

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 540 Chemistry

ISSN:

1525-7770

Publisher:

Taylor & Francis

Language:

English

Submitter:

Christian Leumann

Date Deposited:

19 May 2015 08:52

Last Modified:

19 May 2015 08:52

Publisher DOI:

10.1081/NCN-120022835

PubMed ID:

14565379

Additional Information:

Notes: Department of Chemistry and Biochemistry, University of Bern, Bern, Switzerland buchini@iocunibechFAU - Buchini, Sabrina

Uncontrolled Keywords:

analogue analogues base bases Binding Sites chemical synthesis chemistry DNA inversion Nucleic Acid Conformation nucleoside nucleoside analogues nucleosides Purines Pyrimidines recognition site stability sugar Triplex

BORIS DOI:

10.7892/boris.68568

URI:

https://boris.unibe.ch/id/eprint/68568

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