Ebola virus disease outbreak in Nigeria: Transmission dynamics and rapid control.

Althaus, C L; Low, N; Musa, E O; Shuaib, F; Gsteiger, S (2015). Ebola virus disease outbreak in Nigeria: Transmission dynamics and rapid control. Epidemics, 11, pp. 80-84. Elsevier 10.1016/j.epidem.2015.03.001

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International air travel has already spread Ebola virus disease (EVD) to major cities as part of the unprecedented epidemic that started in Guinea in December 2013. An infected airline passenger arrived in Nigeria on July 20, 2014 and caused an outbreak in Lagos and then Port Harcourt. After a total of 20 reported cases, including 8 deaths, Nigeria was declared EVD free on October 20, 2014. We quantified the impact of early control measures in preventing further spread of EVD in Nigeria and calculated the risk that a single undetected case will cause a new outbreak. We fitted an EVD transmission model to data from the outbreak in Nigeria and estimated the reproduction number of the index case at 9.0 (95% confidence interval [CI]: 5.2-15.6). We also found that the net reproduction number fell below unity 15 days (95% CI: 11-21 days) after the arrival of the index case. Hence, our study illustrates the time window for successful containment of EVD outbreaks caused by infected air travelers.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine

UniBE Contributor:

Althaus, Christian; Low, Nicola and Gsteiger, Sandro

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

1755-4365

Publisher:

Elsevier

Language:

English

Submitter:

Doris Kopp Heim

Date Deposited:

27 May 2015 09:02

Last Modified:

09 Sep 2017 06:31

Publisher DOI:

10.1016/j.epidem.2015.03.001

PubMed ID:

25979285

Uncontrolled Keywords:

Basic reproduction number; Ebola virus disease; Mathematical model; Nigeria; Outbreak

BORIS DOI:

10.7892/boris.69180

URI:

https://boris.unibe.ch/id/eprint/69180

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