Neural change following different memory training approaches in very preterm born children - A pilot study.

Everts, Regula; Mürner-Lavanchy, Ines; Schroth, Gerhard; Steinlin, Maja (2015). Neural change following different memory training approaches in very preterm born children - A pilot study. Developmental neurorehabilitation, 20(1), pp. 1-11. Informa Healthcare 10.3109/17518423.2015.1027010

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There is mixed evidence regarding neural change following cognitive training. Brain activation increase, decrease, or a combination of both may occur. We investigated training-induced neural change using two different memory training approaches.


Very preterm born children (aged 7-12 years) were randomly allocated to a memory strategy training, an intensive working memory practice or a waiting control group. Before and immediately after the trainings and the waiting period, brain activation during a visual working memory task was measured using fMRI and cognitive performance was assessed.


Following both memory trainings, there was a significant decrease of fronto-parietal brain activation and a significant increase of memory performance. In the control group, no neural or performance change occurred after the waiting period.


These pilot data point towards a training-related decrease of brain activation, independent of the training approach. Our data highlight the high training-induced plasticity of the child's brain during development.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine

UniBE Contributor:

Schroth, Gerhard and Steinlin, Maja


600 Technology > 610 Medicine & health




Informa Healthcare




Anette van Dorland

Date Deposited:

26 Jun 2015 13:41

Last Modified:

20 Jul 2022 10:01

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

Children born very preterm; memory; neural change; percent signal change; strategy training; working memory


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