Detection of linear IgE deposits in bullous pemphigoid and mucous membrane pemphigoid: a useful clue for diagnosis

Yayli, S; Pelivani, N; Beltraminelli, H; Wirthmüller, U; Beleznay, Z; Horn, M; Borradori, L (2011). Detection of linear IgE deposits in bullous pemphigoid and mucous membrane pemphigoid: a useful clue for diagnosis. British journal of dermatology, 165(5), pp. 1133-7. Oxford: Wiley-Blackwell 10.1111/j.1365-2133.2011.10481.x

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Bullous pemphigoid (BP) is an autoimmune subepidermal blistering disease of the skin associated with IgG autoantibodies to BP180 and BP230, while mucous membrane pemphigoid (MMP) comprises a heterogeneous group of autoimmune blistering diseases characterized by a predominant mucous membrane involvement and scarring tendency associated with an autoantibody response to various autoantigens, including BP180. While the pathogenicity of IgG autoantibodies to BP180 has been demonstrated in BP, the role of IgE autoantibodies in mediating tissue damage in BP and MMP is unclear.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Institute for Immunology (discontinued)

UniBE Contributor:

Pelivani, Nedzmidin; Beltraminelli, Helmut; Wirthmüller, Urs; Horn, Michael Peter and Borradori, Luca

ISSN:

0007-0963

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:21

Last Modified:

06 Dec 2013 13:27

Publisher DOI:

10.1111/j.1365-2133.2011.10481.x

PubMed ID:

21711326

Web of Science ID:

000297318700032

URI:

https://boris.unibe.ch/id/eprint/6982 (FactScience: 212116)

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