Extraintestinal Crohn's disease mimicking autoimmune inner ear disease: a histopathological approach

Dettmer, Matthias; Hegemann, I; Hegemann, S C A (2011). Extraintestinal Crohn's disease mimicking autoimmune inner ear disease: a histopathological approach. Audiology & neuro-otology, 16(1), pp. 36-40. Basel: Karger 10.1159/000315063

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Patients with autoimmune inner ear disease develop rapidly progressive sensorineural hearing loss over a period of several weeks or months, often accompanied by vestibular loss. This disease can occur as a distinct clinical entity or in association with an underlying autoimmune disorder. Treatment comprises immunosuppression by corticosteroids, cytostatic drugs or tumor necrosis factor- antagonists. We report histopathological and immunohistochemical findings of the inner ear of a patient with a granulomatous inner ear disease suffering from Crohn's disease that was nonresponsive to treatment and who underwent surgery for bilateral cochlear implants.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology > Clinical Pathology

UniBE Contributor:

Dettmer, Matthias

ISSN:

1420-3030

Publisher:

Karger

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:08

Last Modified:

15 Nov 2017 07:43

Publisher DOI:

10.1159/000315063

PubMed ID:

20523038

Web of Science ID:

000291252900005

URI:

https://boris.unibe.ch/id/eprint/706 (FactScience: 200440)

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