Induction of p38, tumour necrosis factor-α and RANTES by mechanical stretching of keratinocytes expressing mutant keratin 10R156H

Obarzanek-Fojt, M; Favre, B; Huber, M; Ryser, S; Moodycliffe, A M; Wipff, P-J; Hinz, B; Hohl, D (2011). Induction of p38, tumour necrosis factor-α and RANTES by mechanical stretching of keratinocytes expressing mutant keratin 10R156H. British journal of dermatology, 164(1), pp. 125-34. Oxford: Wiley-Blackwell 10.1111/j.1365-2133.2010.10013.x

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Epidermolytic hyperkeratosis (bullous congenital ichthyosiform erythroderma), characterized by ichthyotic, rippled hyperkeratosis, erythroderma and skin blistering, is a rare autosomal dominant disease caused by mutations in keratin 1 or keratin 10 (K10) genes. A severe phenotype is caused by a missense mutation in a highly conserved arginine residue at position 156 (R156) in K10.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology

UniBE Contributor:

Favre, Bertrand

ISSN:

0007-0963

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:21

Last Modified:

17 Mar 2015 19:28

Publisher DOI:

10.1111/j.1365-2133.2010.10013.x

PubMed ID:

20804491

Web of Science ID:

000285752000019

URI:

https://boris.unibe.ch/id/eprint/7062 (FactScience: 212211)

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