T1 assessment of hip joint cartilage following intra-articular gadolinium injection: a pilot study

Bittersohl, B; Hosalkar, HS; Kim, YJ; Werlen, S; Trattnig, S; Siebenrock, KA; Mamisch, TC (2010). T1 assessment of hip joint cartilage following intra-articular gadolinium injection: a pilot study. Magnetic resonance in medicine, 64(4), pp. 1200-7. New York, N.Y.: Wiley-Liss 10.1002/mrm.22472

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This pilot study defines the feasibility of cartilage assessment in symptomatic femoroacetabular impingement patients using intra-articular delayed gadolinium-enhanced MRI of cartilage (ia-dGEMRIC). Nine patients were scanned preliminary to study the contrast infiltration process into hip joint cartilage. Twenty-seven patients with symptomatic femoroacetabular impingement were subsequently scanned with intra-articular delayed gadolinium-enhanced MRI of cartilage. These T(1) findings were correlated to morphological findings. Zonal variations were studied. This pilot study demonstrates a significant difference between the pre- and postcontrast T(1) values (P < 0.001) remaining constant for 45 min. We noted higher mean T(1) values in morphologically normal-appearing cartilage than in damaged cartilage, which was statistically significant for all zones except the anterior-superior zone. Intraobserver (0.972) and interobserver correlation coefficients (0.933) were statistically significant. This study outlines the feasibility of intra-articular delayed gadolinium-enhanced MRI of cartilage for assessment of cartilage changes in patients with femoroacetabular impingement. It can also define the topographic extent and differing severities of cartilage damage.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Orthopaedic Surgery

UniBE Contributor:

Bittersohl, Bernd; Siebenrock, Klaus-Arno and Mamisch, Tallal Charles

ISSN:

0740-3194

Publisher:

Wiley-Liss

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:08

Last Modified:

04 May 2014 23:04

Publisher DOI:

10.1002/mrm.22472

PubMed ID:

20872764

Web of Science ID:

000282477100031

URI:

https://boris.unibe.ch/id/eprint/721 (FactScience: 200582)

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