In-vivo phase contrast magnetic resonance angiography of the cerebrovascular system: a comparative study with duplex sonography.

Hsieh, Kety Wha-Vei; Stein, Katja; Mono, Marie-Luise; Kellner-Weldon, Frauke; Verma, Rajeev Kumar; Weisstanner, Christian; Andereggen, Lukas; Reinert, Michael; Gralla, Jan; Schroth, Gerhard; El-Koussy, Marwan (2015). In-vivo phase contrast magnetic resonance angiography of the cerebrovascular system: a comparative study with duplex sonography. Swiss medical weekly, 145(w14155), w14155. EMH Schweizerischer Ärzteverlag 10.4414/smw.2015.14155

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PURPOSE Assessment of the cerebral blood flow (CBF) is crucial in the evaluation of patients with steno-occlusive diseases of the arteries supplying the brain for prediction of stroke risk. Quantitative phase contrast magnetic resonance angiography (PC-MRA) can be utilised for noninvasive quantification of CBF. The aim of this study was to validate in-vivo PC-MRA data by comparing them with colour-coded duplex (CCD) sonography in patients with cerebrovascular disease. METHODS AND MATERIALS We examined 24 consecutive patients (mean age 63 years) with stenosis of arteries supplying the brain using PC-MRA and CCD. Velocities were measured in a total of 209 stenotic and healthy arterial segments (110 extra- and 99 intracranial). RESULTS Moderate to good correlation of velocity measurements between both techniques was observed in all six extracranial and five out of seven intracranial segments (p <0.05). Velocities measured with CCD sonography were generally higher than those obtained by PC-MRA. Reversal of flow direction was detected consistently with both methods. CONCLUSION PC-MRA represents a robust, standardised magnetic resonance imaging technique for blood flow measurements within a reasonable acquisition time, potentially evolving as valuable work-up tool for more precise patient stratification for revascularisation therapy. PC-MRA overcomes relevant weaknesses of CCD in being not operator-dependent and not relying on a bone window to assess the intracranial arteries.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery

UniBE Contributor:

Hsieh, Kety Wha-Vei; Mono, Marie-Luise; Kellner-Weldon, Frauke; Verma, Rajeev Kumar; Weisstanner, Christian; Andereggen, Lukas; Reinert, Michael; Gralla, Jan; Schroth, Gerhard and El-Koussy, Marwan

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1424-7860

Publisher:

EMH Schweizerischer Ärzteverlag

Language:

English

Submitter:

Martin Zbinden

Date Deposited:

05 Oct 2015 08:48

Last Modified:

26 Jun 2016 02:07

Publisher DOI:

10.4414/smw.2015.14155

PubMed ID:

26151805

BORIS DOI:

10.7892/boris.72156

URI:

https://boris.unibe.ch/id/eprint/72156

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