Xenotransplantation of cryopreserved ovarian tissue from patients with ovarian tumors into SCID mice--no evidence of malignant cell contamination

Lotz, Laura; Montag, Markus; van der Ven, Hans; von Wolff, Michael; Mueller, Andreas; Hoffmann, Inge; Wachter, David; Beckmann, Matthias W; Dittrich, Ralf (2011). Xenotransplantation of cryopreserved ovarian tissue from patients with ovarian tumors into SCID mice--no evidence of malignant cell contamination. Fertility and sterility, 95(8), 2612-4.e1. New York, N.Y.: Elsevier 10.1016/j.fertnstert.2011.05.003

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This study examined the possible presence of malignant cells in ovarian cortex from patients with ovarian tumors after xenografting of the ovarian tissue into severe combined immunodeficiency mice. None of the mice presented symptoms of reintroduced malignancy nor did microscopic and immunohistochemical evaluation of the grafts raise any suspicion of residual malignant disease.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology

UniBE Contributor:

von Wolff, Michael

ISSN:

0015-0282

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:21

Last Modified:

05 Dec 2022 14:06

Publisher DOI:

10.1016/j.fertnstert.2011.05.003

PubMed ID:

21621205

Web of Science ID:

000292034100076

URI:

https://boris.unibe.ch/id/eprint/7237 (FactScience: 212425)

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