Corneal Cross-Linking in a 4-Year-Old Child With Keratoconus and Down Syndrome

Sabti, Saad; Tappeiner, Christoph; Früh Epstein, Beatrice (2015). Corneal Cross-Linking in a 4-Year-Old Child With Keratoconus and Down Syndrome. Cornea, 34(9), pp. 1157-1160. Lippincott Williams & Wilkins 10.1097/ICO.0000000000000491

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PURPOSE

To describe the clinical outcome of corneal cross-linking (CXL) in a young child with keratoconus.

METHODS

This is a case report of a young girl with keratoconus with ophthalmologic findings and 3-year follow-up. Follow-up visits included visual acuity measurement, retinoscopy, corneal tomography, and topography.

RESULTS

A girl with Down syndrome was diagnosed with bilateral keratoconus and relative amblyopia at the age of 4 years. The best-corrected near visual acuity was 20/100 binocularly. Corneal tomography showed the following parameters: OD K(max) 47.2 diopters (D), thinnest location 442 μm; OS K(max) 49.6 D, thinnest location 432 μm. Three months later, the keratoconus in the left eye progressed (K(max) 50.2 D, thinnest location 424 μm), and CXL was performed. One year later, CXL was necessary also in the right eye because of progression. The girl was most recently reexamined at the age of 7 years. The corrected near visual acuity was 20/80 in both eyes. The corneal curvature slightly flattened, and the corneal thickness stabilized (OD K(max) 46.8 D, thinnest location 389 μm; OS K(max) 49.4 D, thinnest location 360 μm).

CONCLUSIONS

Onset of keratoconus can occur in early childhood, especially in patients with Down syndrome. In this case, CXL was performed at 4 and 5 years of age without complications and stopped further keratoconus progression.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

UniBE Contributor:

Sabti, Saad; Tappeiner, Christoph and Früh Epstein, Beatrice

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0277-3740

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Christoph Tappeiner

Date Deposited:

04 Dec 2015 08:38

Last Modified:

03 Nov 2016 15:18

Publisher DOI:

10.1097/ICO.0000000000000491

PubMed ID:

26165788

BORIS DOI:

10.7892/boris.73384

URI:

https://boris.unibe.ch/id/eprint/73384

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