Schlatter, Bettina; Beck, Marco; Früh Epstein, Beatrice; Tappeiner, Christoph; Zinkernagel, Martin (2015). Evaluation of scleral and corneal thickness in keratoconus patients. Journal of cataract and refractive surgery, 41(5), pp. 1073-1080. Elsevier 10.1016/j.jcrs.2014.08.035
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PURPOSE
To determine whether the scleral stroma is affected as much as the corneal stroma in keratoconus.
SETTING
University Eye Clinic, Bern, Switzerland.
DESIGN
Comparative case-control study.
METHODS
Eyes with keratoconus (keratoconus group) and eyes of age-, sex-, and axial length-matched controls (control group) were analyzed. Corneal videokeratometry and pachymetry were performed using a Scheimpflug tomographer (Pentacam). For measurements of the peripheral cornea and the anterior sclera, a spectral-domain anterior segment optical coherence tomography device (Spectralis) was used.
RESULTS
The study group comprised 51 eyes and the control group, 50 eyes. The mean central corneal thickness in the keratoconus group was statistically significantly lower than in the control group (447.8 μm ± 57.8 [SD] versus 550.5 ± 35.5 μm) (P < .0001). No significant difference in the mean anterior scleral thickness was found between the keratoconus group and the control group (479.1 ± 43.7 μm versus 474.2 ± 43.0 μm) (P =.57).
CONCLUSION
Although corneal thinning was observed in keratoconus patients, the anterior scleral stroma thickness in these patients seemed to be similar to that in healthy control eyes.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology 04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy |
UniBE Contributor: |
Beck, Marco, Früh Epstein, Beatrice, Tappeiner, Christoph, Zinkernagel, Martin Sebastian |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0886-3350 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Christoph Tappeiner |
Date Deposited: |
03 Dec 2015 15:14 |
Last Modified: |
02 Mar 2023 23:26 |
Publisher DOI: |
10.1016/j.jcrs.2014.08.035 |
PubMed ID: |
25935338 |
BORIS DOI: |
10.7892/boris.73385 |
URI: |
https://boris.unibe.ch/id/eprint/73385 |
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