Evaluation of scleral and corneal thickness in keratoconus patients

Schlatter, Bettina; Beck, Marco; Früh Epstein, Beatrice; Tappeiner, Christoph; Zinkernagel, Martin (2015). Evaluation of scleral and corneal thickness in keratoconus patients. Journal of cataract and refractive surgery, 41(5), pp. 1073-1080. Elsevier 10.1016/j.jcrs.2014.08.035

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PURPOSE To determine whether the scleral stroma is affected as much as the corneal stroma in keratoconus. SETTING University Eye Clinic, Bern, Switzerland. DESIGN Comparative case-control study. METHODS Eyes with keratoconus (keratoconus group) and eyes of age-, sex-, and axial length-matched controls (control group) were analyzed. Corneal videokeratometry and pachymetry were performed using a Scheimpflug tomographer (Pentacam). For measurements of the peripheral cornea and the anterior sclera, a spectral-domain anterior segment optical coherence tomography device (Spectralis) was used. RESULTS The study group comprised 51 eyes and the control group, 50 eyes. The mean central corneal thickness in the keratoconus group was statistically significantly lower than in the control group (447.8 μm ± 57.8 [SD] versus 550.5 ± 35.5 μm) (P < .0001). No significant difference in the mean anterior scleral thickness was found between the keratoconus group and the control group (479.1 ± 43.7 μm versus 474.2 ± 43.0 μm) (P =.57). CONCLUSION Although corneal thinning was observed in keratoconus patients, the anterior scleral stroma thickness in these patients seemed to be similar to that in healthy control eyes.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy

UniBE Contributor:

Beck, Marco; Früh Epstein, Beatrice; Tappeiner, Christoph and Zinkernagel, Martin

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0886-3350

Publisher:

Elsevier

Language:

English

Submitter:

Christoph Tappeiner

Date Deposited:

03 Dec 2015 15:14

Last Modified:

03 Dec 2015 15:14

Publisher DOI:

10.1016/j.jcrs.2014.08.035

PubMed ID:

25935338

BORIS DOI:

10.7892/boris.73385

URI:

https://boris.unibe.ch/id/eprint/73385

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