Superior Vena Cava Syndrome (SVCS) in Thoracic Malignancies

Lepper, Philipp M; Ott, Sebastian R; Hoppe, Hanno; Schumann, Christian; Stammberger, Uz; Bugalho, Antonio; Frese, Steffen; Schmücking, Michael; Blumstein, Norbert M; Diehm, Nicolas; Bals, Robert; Hamacher, Jürg (2011). Superior Vena Cava Syndrome (SVCS) in Thoracic Malignancies. Respiratory care, 56(5), pp. 653-66. Irving, Tex.: Daedalus Enterprises 10.4187/respcare.00947

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The superior vena cava syndrome (SVCS) comprises various symptoms due to occlusion of the SVC, which can be easily obstructed by pathological conditions (eg, lung cancer, due to the low internal venous pressure within rigid structures of the thorax [trachea, right bronchus, aorta]). The resulting increased venous pressure in the upper body may cause edema of the head, neck, and upper extremities, often associated with cyanosis, plethora, and distended subcutaneous vessels. Despite the often striking clinical presentation, SVCS itself is usually not a life-threatening condition. Currently, randomized controlled trials on many clinically important aspects of SVCS are lacking. This review gives an interdisciplinary overview of the pathophysiology, etiology, clinical manifestations, diagnosis, and treatment of malignant SVCS.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Pneumology 04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Thoracic Surgery 04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology 04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Angiology
UniBE Contributor:	Ott, Sebastian Robert, Hoppe, Hanno, Frese, Steffen R., Schmücking, Michael, Diehm, Nicolas Alexander
ISSN:	0020-1324
Publisher:	Daedalus Enterprises
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:08
Last Modified:	05 Dec 2022 14:00
Publisher DOI:	10.4187/respcare.00947
PubMed ID:	21276318
Web of Science ID:	000291194200013
URI:	https://boris.unibe.ch/id/eprint/734 (FactScience: 200653)