Low statin use in adults hospitalized with acute coronary syndrome.

Selby, Kevin; Nanchen, David; Auer, Reto; Gencer, Baris; Räber, Lorenz; Klingenberg, Roland; Blum, Manuel; Marques-Vidal, Pedro; Cornuz, Jacques; Muller, Olivier; Vogt, Pierre; Jüni, Peter; Matter, Christian M; Windecker, Stephan; Lüscher, Thomas F; Mach, François; Rodondi, Nicolas (2015). Low statin use in adults hospitalized with acute coronary syndrome. Preventive medicine, 77, pp. 131-136. Elsevier 10.1016/j.ypmed.2015.05.012

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OBJECTIVE To assess recommended and actual use of statins in primary prevention of cardiovascular disease (CVD) based on clinical prediction scores in adults who develop their first acute coronary syndrome (ACS). METHOD Cross-sectional study of 3172 adults without previous CVD hospitalized with ACS at 4 university centers in Switzerland. The number of participants eligible for statins before hospitalization was estimated based on the European Society of Cardiology (ESC) guidelines and compared to the observed number of participants on statins at hospital entry. RESULTS Overall, 1171 (37%) participants were classified as high-risk (10-year risk of cardiovascular mortality ≥5% or diabetes); 1025 (32%) as intermediate risk (10-year risk <5% but ≥1%); and 976 (31%) as low risk (10-year risk <1%). Before hospitalization, 516 (16%) were on statins; among high-risk participants, only 236 of 1171 (20%) were on statins. If ESC primary prevention guidelines had been fully implemented, an additional 845 high-risk adults (27% of the whole sample) would have been eligible for statins before hospitalization. CONCLUSION Although statins are recommended for primary prevention in high-risk adults, only one-fifth of them are on statins when hospitalized for a first ACS.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine > Centre of Competence for General Internal Medicine
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine
04 Faculty of Medicine > Pre-clinic Human Medicine > CTU Bern
04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine

UniBE Contributor:

Räber, Lorenz; Blum, Manuel; Jüni, Peter; Windecker, Stephan and Rodondi, Nicolas

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

0091-7435

Publisher:

Elsevier

Language:

English

Submitter:

Doris Kopp Heim

Date Deposited:

26 Nov 2015 15:10

Last Modified:

27 Nov 2015 11:37

Publisher DOI:

10.1016/j.ypmed.2015.05.012

PubMed ID:

26007299

Uncontrolled Keywords:

Acute coronary syndrome; Cardiovascular risk scores; Primary prevention Statins

BORIS DOI:

10.7892/boris.73439

URI:

https://boris.unibe.ch/id/eprint/73439

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