Systemic vascular dysfunction in patients with chronic mountain sickness

Rimoldi, Stefano F; Rexhaj, Emrush; Pratali, Lorenza; Bailey, Damian M; Hutter, Damian; Faita, Francesco; Salmòn, Carlos Salinas; Villena, Mercedes; Nicod, Pascal; Allemann, Yves; Scherrer, Urs; Sartori, Claudio (2012). Systemic vascular dysfunction in patients with chronic mountain sickness. Chest, 141(1), pp. 139-46. Northbrook, Ill.: American College of Chest Physicians 10.1378/chest.11-0342

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Chronic mountain sickness (CMS) is a major public health problem characterized by exaggerated hypoxemia and erythrocytosis. In more advanced stages, patients with CMS often present with functional and structural changes of the pulmonary circulation, but there is little information on the systemic circulation. In patients with diseases associated with chronic hypoxemia at low altitude, systemic vascular function is altered. We hypothesized that patients with CMS have systemic vascular dysfunction that may predispose them to increased systemic cardiovascular morbidity.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine

UniBE Contributor:

Rimoldi, Stefano, Rexhaj, Emrush, Hutter, Damian Marco, Allemann, Yves, Scherrer, Urs, Sartori, Claudio




American College of Chest Physicians




Anette van Dorland

Date Deposited:

04 Oct 2013 14:22

Last Modified:

02 Mar 2023 23:20

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Additional Information:

Rimoldi, Stefano F;Rexhaj, Emrush;Pratali, Lorenza;Bailey, Damian M;Hutter, Damian;Faita, Francesco;Salmon, Carlos Salinas;Villena, Mercedes;Nicod, Pascal;Allemann, Yves;Scherrer, Urs;Sartori, Claudio;Chest. 2012 Jan;141(1):139-46. doi: 10.1378/chest.11-0342. Epub 2011 Jun 23.

URI: (FactScience: 212598)

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