Health care use of long-term survivors of childhood cancer: the British Childhood Cancer Survivor Study

Rebholz, Cornelia E; Reulen, Raoul C; Toogood, Andrew A; Frobisher, Clare; Lancashire, Emma R; Winter, David L; Kuehni, Claudia E; Hawkins, Michael M (2011). Health care use of long-term survivors of childhood cancer: the British Childhood Cancer Survivor Study. Journal of clinical oncology, 29(31), pp. 4181-4188. Alexandria, Va.: American Society of Clinical Oncology 10.1200/JCO.2011.36.5619

[img] Text
Rebholz JClinOncol 2011.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (94kB) | Request a copy

Purpose Survivors of childhood cancer are at high risk of chronic conditions, but few studies investigated whether this translates into increased health care utilization. We compared health care service utilization between childhood cancer survivors and the general British population and investigated potential risk factors.

Methods We used data from the British Childhood Cancer Survivor Study, a population-based cohort of 17,981 individuals diagnosed with childhood cancer (1940-1991) and surviving ≥ 5 years. Frequency of talks to a doctor, hospital outpatient visits, and day-patient and inpatient hospitalizations were ascertained by questionnaire in 10,483 survivors and were compared with the General Household Survey 2002 data by using logistic regression.

Results Among survivors, 16.5% had talked to a doctor in the last 2 weeks, 25.5% had attended the outpatient department of a hospital in the last 3 months, 11.9% had been hospitalized as a day patient in the last 12 months, and 9.8% had been hospitalized as an inpatient in the last 12 months. Survivors had talked slightly more often to a doctor than the general population (odds ratio [OR], 1.2; 95% CI, 1.1 to 1.3) and experienced increased hospital outpatient visits (OR, 2.5; 95% CI, 2.3 to 2.8), day-patient hospitalizations (OR, 1.4; 95% CI, 1.3 to 1.6) and inpatient hospitalizations (OR, 1.9; 95% CI, 1.7 to 2.2). Survivors of Hodgkin's lymphoma, neuroblastoma, and Wilms tumor had the highest ORs for day-patient care, whereas survivors of CNS tumors and bone sarcomas had the highest OR for outpatient and inpatient care. The OR of health care use did not vary significantly with age of survivor.

Conclusion We have quantified how excess morbidity experienced by survivors of childhood cancer translates into increased use of health care facilities.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

UniBE Contributor:

Rebholz, Cornelia and Kühni, Claudia




American Society of Clinical Oncology




Factscience Import

Date Deposited:

04 Oct 2013 14:22

Last Modified:

05 Dec 2022 14:06

Publisher DOI:


PubMed ID:


Web of Science ID:




URI: (FactScience: 212604)

Actions (login required)

Edit item Edit item
Provide Feedback