Rapid drop in the reproduction number during the Ebola outbreak in the Democratic Republic of Congo.

Althaus, Christian L (2015). Rapid drop in the reproduction number during the Ebola outbreak in the Democratic Republic of Congo. PeerJ, 3, e1418. PeerJ, Ltd 10.7717/peerj.1418

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The Democratic Republic of Congo (DRC) experienced a confined rural outbreak of Ebola virus disease (EVD) with 69 reported cases from July to October 2014. Understanding the transmission dynamics during the outbreak can provide important information for anticipating and controlling future EVD epidemics. I fitted an EVD transmission model to previously published data of this outbreak and estimated the basic reproduction number R 0 = 5.2 (95% CI [4.0-6.7]). The model suggests that the net reproduction number Rt fell below unity 28 days (95% CI [25-34] days) after the onset of symptoms in the index case. This study adds to previous epidemiological descriptions of the 2014 EVD outbreak in DRC, and is consistent with the notion that a rapid implementation of control interventions helped reduce further spread.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine

UniBE Contributor:

Althaus, Christian

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

2167-8359

Publisher:

PeerJ, Ltd

Language:

English

Submitter:

Doris Kopp Heim

Date Deposited:

08 Dec 2015 14:28

Last Modified:

21 Sep 2017 02:52

Publisher DOI:

10.7717/peerj.1418

PubMed ID:

26618087

Uncontrolled Keywords:

Basic reproduction number Democratic Republic of Congo Ebola virus disease Mathematical model Outbreak

BORIS DOI:

10.7892/boris.74017

URI:

https://boris.unibe.ch/id/eprint/74017

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